Aberfeldie hosts Avondale Heights at Clifton Park in a match that the Abers will need to win if they are to finish in the top three.
Aberfeldie recorded a five-point win over the third placed Strathmore last weekend, putting them within four points of taking their spot on the ladder.
While it is still unlikely for this to happen, Aberfeldie will be determined to win all their remaining games just in case.
The two sides last played each other in a thriller back on ANZAC Day.
Aberfeldie came out on top by three points with Ben Ronke (four goals) and(Karl Brown (three goals) instrumental in the victory.
Avondale Heights are now officially confirmed to finish in last place and be relegated, having won just the one game so far and will be looking to add a couple more consolation wins or competitive performances before they drop down to Division One at the season's end.
Greenvale will take on East Keilor at Greenvale Recreation Reserve in what is a must win match for the hosts if they are to lock in a finals spot.
There are just two points separating Greenvale in fifth spot from Airport West in sixth and as a result, Greenvale can not afford to lose this one.
When these two teams last met it was Greenvale who came out on top by one-point in a high-scoring thriller.
Ryan Townsend had a best on ground performance for Greenvale in that game, while Lachlan Smart booted six goals for East Keilor.
East Keilor are currently sitting in second last position on the ladder, and while relegation is off the table they would still like to secure some more wins and disrupt the top five.
Airport West takes on Keilor at Hansen Reserve in a match that the hosts will be looking to cause an upset in as they continue to hunt for a spot in the finals.
The Eagles claimed a big win over fifth place Greenvale last weekend to keep their finals chances alive.
However, their run home isn’t easy as they play both top two teams in their last three matches, meaning they will likely need to claim at least one upset to make the finals if the Jets win this weekend.
The last time the two sides came up against each other was back in Round 2 when Keilor were victorious by 51 points.
Nick O’Kearney and James Bailey starred for Keilor in that match and as a result, Airport West will need to find a way to shut them down this time around.
Keilor go into this match as heavy favourites having not lost a match yet this season.
They did however, have a shaky game a couple weeks ago which will give Airport West hope for an upset, while also meaning Keilor will need to make sure they are ready for a hungry Airport West.
Deer Park will battle it out against Strathmore at John McLeod Reserve, the visitors will be hunting a win to try and lock in a top three finish.
The last time the two sides met it was Strathmore who were victorious coming out on top by 26 points.
Trent Dumont starred in that match and will be someone Deer Park will pay close attention to this time around.
Strathmore had a disappointing loss to Aberfeldie last week going down by five points.
The result means that Strathmore will want to win all their remaining games to make sure Aberfeldie doesn’t overtake them on the ladder for the double chance.
Pascoe Vale will face off against Essendon Doutta Stars at Raeburn Reserve in a match that is relatively low stakes.
Pascoe Vale have almost locked in a top two finish, as they pretty much only need one more victory to make it official.
The Panthers will be aiming to get that done this week as they look to build as much momentum as possible before they hit the finals in three weeks time.
These two teams met back in Round 1 in a game that was easily won by Pascoe Vale with a margin of 67 points.
Sunny Brazier was prominent in that game, booting five majors.
Douttas currently sit in seventh spot on the ladder and will be looking to finish off the year as strongly as possible.
Oak Park takes on Rupertswood at JP Fawkner Reserve in a match the visitors will be desperate to win to avoid relegation.
Oak Park go into this match with no pressure on them as they have now secured a finals berth and will instead be using their last two matches to build some momentum before heading into the finals.
The two sides met last back in Round 4 in a match that Oak Park won by 13 points.
Anthony DeLorenzi was huge in that game for the Oakers kicking three crucial goals and gathering plenty of possessions.
Rupertswood are currently second last and in the relegation zone.
They will know that a loss this week will almost certainly mean they will be relegated down to Division Two next season and as a result, will be using all their energy across the last two weeks to survive the drop.
Roxburgh Park hosts St Albans at Lakeside Reserve in a match the hosts would like to win to save them from the threat of relegation.
Roxburgh Park are currently just one win above the relegation zone and will know that at least one win in these last two games will make them 100 per cent safe, while a loss will leave their survival up in the air.
When these sides last met it was St Albans who came out on top by 21 points.
However, if not for bad kicking the Saints would’ve won by a lot more and as such, Roxy will need to find a way to shut down the Saints attacking prowess this time around.
The Saints have very little pressure on them going into this game as they are almost certain to finish in fourth position now.
The focus for St Albans now will just be to head into finals in as strong a form as possible and bounce back from a big loss.
Tullamarine will face off against Craigieburn in a battle for sixth spot at Leo Dineen Reserve.
Tullamarine are officially out of the finals race now having lost to Oak Park last week.
They will now be turning their attention to holding on to sixth spot which is the highest position they can finish.
These two sides met back in Round 9 in a match where Tulla came out victorious by 22 points.
Joel Flanigan was huge in that match scoring five goals and will be someone Craigieburn will be looking to shut down this time around.
Craigieburn secured their first win since Round 6 last week, defeating Rupertswood by 26 points to officially secure a spot in Division One for next year.
The Eagles will now have their sights set on finishing as high as possible on the ladder which is sixth place by beating Tulla this weekend.
Maribyrnong Park will battle it out against West Coburg at Monk Oval in what looms as a potential grand final preview.
Marby Park have been arguably the most in-form team in Division One having not lost since all the way back in Round 4.
Their last seven matches have all been wins with a margin of over 70 points.
West Coburg are also on a long winning streak having only lost the one match this year all the way back in Round 2.
West Coburg will need a win to cement a first place finish while also potentially gaining a psychological advantage over Marby going into the finals.
These two sides played each other back in Round 1 of this season, in a match that was won by West Coburg with a margin of 16 points.
This time around, the match should be even more thrilling as the two best sides of the season so far go head to head.
Moonee Valley plays Keilor Park at Ormond Park in a match that could see the hosts officially become safe from relegation.
Moonee Valley currently sit in ninth spot just outside the relegation zone.
They will know that a win this week over last placed Keilor Park will almost certainly secure them a position in Division One next season.
When these sides last met, Moonee Valley were victorious by 30 points.
Charles Aitken starred in that game for the Valley kicking two goals and gathering up plenty of disposals.
This week's match is Keilor Park’s last of the season and last in Division One for some time as they are confirmed to be relegated.
As a result, they are just playing for pride and will be looking to finish their season off on a positive note.
Coburg Districts will take on Westmeadows at Cole Reserve in a must-win clash for the hosts if they are to keep their finals hopes alive.
A disappointing loss to Hadfield two weeks ago has made Coburg Districts' finals chances harder as they now need to win their two remaining games and hope other results fall their way.
The Districts however, will just be focusing on what they can achieve which is to win this weekend.
The last time these two sides faced each other was back in Round 2 in a low scoring thriller that saw Westmeadows come out on top by five points.
It was a match that the Districts probably should’ve won but didn’t due to their inaccurate goalkicking.
Westmeadows go into this week's match with no pressure as they can finish no lower or no higher than third place on the ladder.
It’ll be all about building momentum for the Tigers in their last two matches before finals.
Sunbury Kangaroos hosts the Northern Saints at Eric Boardman Reserve in a match the visitors need to win to hold onto their top four position.
The Kangaroos are playing their final game of the season this week with the percentage differential to the top four too big to wrangle.
The last time these two teams met was back in Round 10, where the Saints were victorious by 66 points.
Khoder Taleb (seven goals) and Nick Bruno (five goals) were huge in that match and as such, the Kangaroos will need to shut those two down this weekend if they are to have any chance.
The Northern Saints know that all they need to do is win their last two games of the season and they will play finals.
Hadfield plays East Sunbury at Martin Reserve in what should be a relatively straightforward win for the hosts.
While Hadfield’s chances of playing finals are now over, they will still be looking for some consolation wins to end the season on a high note.
This week's match should prove the perfect game for the Hawks to claim a big win before the season ends.
Hadfield played East Sunbury back in Round 7 this season in a match the Hawks won by 59 points.
Sam Godden kicked four goals in that match in a man of the match performance from the Hadfield star.
East Sunbury have nothing to play for but pride this weekend, as they look to avoid going a full season without a win.
Glenroy will face off against Taylors Lakes at Sewell Reserve this weekend.
When these two sides last met it was Taylors Lakers who were victorious by 38 points.
Ben Weightman starred for the Lakers in that game, booting eight majors.
Taylors Lakes will go into this week's match attempting to regain the top spot as Burnside have the bye this weekend.
The Lakers will know a final showdown for top spot awaits them in the last round so they will be looking to take as much momentum as possible into that clash.
THIS WEEKEND’S FIXTURES
AIRPORT WEST v KEILOR
Saturday 2:15pm at Hansen Reserve
ABERFELDIE v AVONDALE HEIGHTS
Saturday 2:15pm at Clifton Park
GREENVALE v EAST KEILOR
Saturday 2:15pm at Greenvale Recreation Reserve
DEER PARK v STRATHMORE
Saturday 2:15pm at John McLeod Reserve
PASCOE VALE v ESSENDON DOUTTA STARS
Saturday 2:15pm at Raeburn Reserve
OAK PARK v RUPERTSWOOD
Saturday 2:15pm at JP Fawkner Reserve
ROXBURGH PARK v ST ALBANS
Saturday 2:15pm at Lakeside Reserve
TULLAMARINE v CRAIGIEBURN
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Saturday 2:15pm at Leo Dineen Reserve
MOONEE VALLEY v KEILOR PARK
Saturday 2:15pm at Ormond Park
MARIBYRNONG PARK v WEST COBURG
Saturday 2:15pm at Monk Oval
COBURG DISTRICTS v WESTMEADOWS
Saturday 2:15pm at Cole Reserve
HADFIELD v EAST SUNBURY
Saturday 2:15pm at Martin Reserve
SUNBURY KANGAROOS v NORTHERN SAINTS
Saturday 2:15pm at Eric Boardman Reserve
GLENROY v TAYLORS LAKES
Saturday 2:15pm at Sewell Reserve